Side Effects of Axitinib

Side Effects of Axitinib

Understanding the possible side effects that may occur during treatment with axitinib can help patients enhance self-monitoring awareness and improve treatment adherence.

Serious Side Effects

More Common Serious Side Effects

Blood and Bleeding-Related

Bleeding gums, nosebleeds, coughing up blood, increased menstrual flow or vaginal bleeding, red or black tarry stools, red or dark brown urine.

Digestive System

Clay-colored stools, constipation, dry mouth, decreased appetite, metallic taste, nausea, abdominal pain or tenderness, vomiting.

Nervous System

Confusion, dizziness, fainting, headache, slurred speech, paralysis, lightheadedness, tingling in the hands and feet.

Cardiovascular System

Chest tightness, unusually slow or fast heartbeat, swelling of the feet or lower legs.

Respiratory System

Difficulty breathing, shortness of breath.

Skin and Appendages

Dry skin and hair, hair loss, skin itching or rash, redness/swelling/pain of the skin, peeling skin on hands and feet, skin ulcers, increased skin wrinkling.

Endocrine and Metabolic

Feeling cold, thirst, weight loss or gain, sunken eyes.

Urinary and Reproductive System

Cloudy urine, decreased urine output, frequent urination.

Sensory System

Blurred vision, ringing in the ears, yellowing of the eyes or skin.

Less Common Serious Side Effects

Blood and Bleeding-Related

Rectal bleeding, bloody/black or tarry stools, unusual bleeding or bruising, vomit that looks like coffee grounds.

Digestive System

Heartburn, indigestion, severe abdominal pain/cramping/burning sensation, ulcers or white patches on the lips, tongue, or inside the mouth, discomfort or swelling around the anus.

Nervous System

Extreme sleepiness, inability to speak, numbness or tingling in the face, arms, hands, or legs, seizures, sudden severe headache, slurred speech, sudden loss of coordination, sudden unclear speech, difficulty speaking, thinking, or walking, weakness on one side of the body.

Cardiovascular System

Chest pain or discomfort, pain in the chest, groin, or legs, pain or discomfort in the arms, jaw, back, or neck.

Other Side Effects

More Common Other Side Effects

Belching, changes in taste, cough, cracked lips, decreased appetite, diarrhea, difficulty moving, joint pain or swelling, fatigue, loss of taste, muscle aches, pain in the arms or legs, sore throat, stomach discomfort or upset, swelling or inflammation of the mouth, upper abdominal pain, changes in voice.

Less Common Other Side Effects

Burning sensation of the tongue, persistent ringing or other unexplained noises in the ears, skin flushing or redness, hearing loss, thinning hair, unusual warmth of the skin.