Precautions for the use of medications in Rheumatology

1. Low-dose vs. short-term use of hormonal drugs

Hormones should be administered at the lowest effective dose and for the shortest duration possible. If prolonged use of low-dose corticosteroids is necessary, patients should undergo continuous monitoring to mitigate potential adverse events.

2. Focus on cumulative usage

Cumulative corticosteroid dosage was significantly associated with the risk of serious adverse events. The higher the cumulative dose of hormones, the higher the risk of these outcomes. Patients should be closely monitored for cumulative hormone dosage and avoid overdose.

3. Medication for special populations

Patients with diabetes or prediabetes should minimize hormone use whenever feasible. Those with chronic kidney disease or a history of gastrointestinal bleeding should attempt to steer clear of non-steroidal anti-inflammatory pain relievers.

4. Monitoring and evaluation

Patients receiving rheumatology medications should undergo regular monitoring for any changes in their condition, drug reactions, and the occurrence of adverse effects.

Particularly for individuals on long-term hormone or disease-modifying antirheumatic drugs (DMARDs), parameters such as blood tests, liver and kidney function, etc., should be closely observed.